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. 2014 Aug 15;4:6085. doi: 10.1038/srep06085

Table 1. Percentage error (root mean square error) in the simulated odds ratio (OR) with confounder (simulation size = 10,000).

Significance criterion (p < 0.05) N = 200 N = 500 N = 1,000
  ORx ORx,z ORx ' ORx,z ' % indicating confounding effect ORx ORx,z ORx ' ORx,z ' % indicating confounding effect ORx ORx,z ORx ' ORx,z ' % indicating confounding effect
Corr (X, Z)                              
0.1 2.50 (0.16) −0.46 (0.16) 2.36 (0.17) 1.69 (0.17) 10.72 1.14 (0.10) −1.01 (0.10) 1.35 (0.10) 0.68 (0.10) 19.51 1.17 (0.07) −0.44 (0.07) 1.27 (0.07) 0.63 (0.07) 34.67
0.2 3.40 (0.17) −3.15 (0.17) 3.10 (0.17) 1.61 (0.17) 10.21 2.82 (0.11) −1.69 (0.10) 2.36 (0.11) 0.98 (0.10) 19.32 2.54 (0.08) −0.82 (0.07) 2.22 (0.08) 0.93 (0.07) 33.18
0.3 4.44 (0.18) −5.21 (0.18) 4.28 (0.18) 2.03 (0.18) 9.30 3.45 (0.11) −3.43 (0.11) 3.50 (0.11) 1.43 (0.11) 18.58 3.22 (0.08) −1.97 (0.07) 3.30 (0.08) 1.32 (0.08) 32.64
0.4 5.38 (0.18) −8.10 (0.20) 5.59 (0.18) 2.74 (0.18) 9.46 4.61 (0.12) −5.00 (0.11) 4.63 (0.12) 1.80 (0.11) 17.69 4.35 (0.09) −2.85 (0.08) 4.38 (0.09) 1.75 (0.08) 30.18
0.5 6.34 (0.19) −10.79 (0.23) 6.45 (0.19) 2.82 (0.19) 9.17 5.56 (0.12) −6.93 (0.13) 5.61 (0.12) 2.09 (0.12) 16.17 5.28 (0.09) −4.18 (0.08) 5.36 (0.10) 1.97 (0.08) 27.46

Data are simulated from the model Prob(Y = 1)/Prob(Y = 0) = exp(0.1)X + exp(0.1)Z.

Percentage error and root mean square error in correct decision are underlined.

ORx: Percentage of OR of X where Z was not adjusted and the criterion has indicated a confounding effect.

ORx,z: Percentage of OR of X where Z was adjusted and the criterion has indicated a confounding effect.

ORx': Percentage of OR of X where Z was not adjusted and the criterion has not indicated a confounding effect.

ORx,z': Percentage of OR of X where Z was adjusted and the criterion has not indicated a confounding effect.

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