. 2014 Aug 22;4:6159. doi: 10.1038/srep06159

Table 3. MTHFR mRNA expression by the genotypes of SNPs, using data from the HapMap^a.

Population	C667T (rs1801133)					A1298C (rs1801131)
Population	genotypes	No.	Mean ± SD	P^b	P_trend^c	genotypes	No.	Mean ± SD	P^b	P_trend^c
CEU	CC	48	6.14 ± 0.10		0.904	AA	41	6.12 ± 0.09		0.139
	CT	37	6.14 ± 0.09	0.924		AC	36	6.15 ± 0.10	0.069
	TT	5	6.12 ± 0.09	0.685		CC	13	6.16 ± 0.09	0.163
	Dominant	42	6.14 ± 0.09	0.983		Dominant	49	6.15 ± 0.09	0.046
YRI^d	CC	70	6.20 ± 0.08		0.329	AA	71	6.20 ± 0.07		0.197
	CT	19	6.19 ± 0.06	0.651		AC	17	6.19 ± 0.09	0.504
	TT	1	6.09	0.171		CC	1	6.07	0.074
	Dominant	20	6.19 ± 0.06	0.470		Dominant	18	6.18 ± 0.09	0.317
Asian^d	CC	30	6.18 ± 0.08		0.116	AA	59	6.22 ± 0.10		0.074
	CT	40	6.21 ± 0.09	0.120		AC	28	6.17 ± 0.09	0.024
	TT	19	6.23 ± 0.11	0.052		CC	3	6.20 ± 0.06	0.814
	Dominant	59	6.22 ± 0.10	0.057		Dominant	31	6.17 ± 0.08	0.028
All^d	CC	148	6.17 ± 0.09		0.360	AA	171	6.19 ± 0.09		0.186
	CT	96	6.18 ± 0.09	0.732		AC	81	6.17 ± 0.09	0.107
	TT	25	6.20 ± 0.12	0.156		CC	17	6.16 ± 0.09	0.261
	Dominant	121	6.18 ± 0.10	0.422		Dominant	98	6.16 ± 0.09	0.069

^aGenotyping data and mRNA expression levels for MTHFR by genotypes were obtained from the HapMap phase II release 23 data from EBV-transformed lymphoblastoid cell lines from 270 individuals.

^bTwo-side Student's t test within the stratum.

^cP values for the trend test of MTHFR mRNA expression among 3 genotypes for each SNP from a general linear model.

^dThere were missing data because genotyping data were not available.

Table 3. MTHFR mRNA expression by the genotypes of SNPs, using data from the HapMapa.

Table 3. MTHFR mRNA expression by the genotypes of SNPs, using data from the HapMap^a.