Table 1.
Model parameter values in mathematical model*
Model parameters | Nodal type (AP) |
Atrial type (AP) |
Ventricular type (AP) |
---|---|---|---|
ECaL, mV | 47 | 47 | 47 |
gCaL, nS | 11.0140 | 12.5874 | 12.5874 |
k1 | 0.9 | 1.1 | 1.8 |
k2 | 1.0 | 1.3 | 2.2 |
gHCN,Na, nS | 0.0529 | 0.0529 | 0.0529 |
gHCN,K, nS | 0.0851 | 0.0851 | 0.0851 |
gto,UF, nS | 0.3346 | 1.3382 | 0.6691 |
gto,F, nS | 0.1338 | 0.5352 | 0.2676 |
gto,S, nS | 0.2091 | 0.8364 | 0.4182 |
gKs, nS | 0.0411 | 0.2057 | 0.4114 |
gb,Ca, nS | 0 | 0 | 0 |
gb,Na, nS | 0.170 | 0.122 | 0.122 |
gb,K, nS | 0.035 | 0.025 | 0.025 |
gCaT, nS | 0 | 0 | 0 |
gKl, nS | 0 | 0.6075 | 2.2275 |
gKr, nS | 1.5319 | 0.6383 | 0.6383 |
gNa,1.5, nS | 0.0059 | 0.0237 | 0.0296 |
gNa,1.1, nS | 0.0059 | 0.0237 | 0.0296 |
gst, nS | 0 | 0 | 0 |
gsus, nS | 0 | 0 | 0 |
See glossary of Kharche et al's9 model for detailed explanation of each channel.
Note. Adapted from “Dual modulation of the mitochondrial permeability transition pore and redox signaling synergistically promotes cardiomyocyte differentiation from pluripotent stem cells,” by S.W. Cho, J.S. Park, H.J. Heo, S.W. Park, S. Song, I. Kim et al., 2014, J Am Heart Assoc, 3, e000693. Copyright 2014 The Authors. Reprinted with permission.
AP; action potential.