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. 2016 Jan 8;5(1):48–55. doi: 10.1016/j.imr.2015.12.005

Table 3.

Effect of Tinospora cordifolia extract on the activities of membrane-bound ATPases in Cd-induced nephrotoxicity

Membrane-bound ATPases Group I Group II Group III Group IV
Na+ K+ ATPase 9.03 ± 0.3 8.38 ± 0.06* 9.22 ± 0.61 8.76 ± 0.09
Ca2+ ATPase 7.48 ± 0.64 5.38 ± 0.25* 7.55 ± 0.42 6.94 ± 0.31
Mg2+ ATPase 7.91 ± 0.15 5.9 ± 0.04* 7.97 ± 0.52 7.53 ± 1.20

Data are presented as mean ± standard error (n = 6) and nmols of pi-liberated/mg of protein.

*

p < 0.001, compared to control.

p < 0.001, compared to the Cd-treated group.

Not significant as compared to control.

Cd, cadmium; Group I, Control; Group II, treated with Cd chloride [5 mg/kg body weight (BW)]; Group III, treated with Tinospora cordifolia-stem methanolic extract (TCE; 100 mg/kg BW); Group IV; treated with Cd chloride (5 mg/kg BW) and TCE (100 mg/kg BW); Cd + TCE.