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. 2016 Jan 13;37(2):396–412. doi: 10.1177/0271678X15626718

Figure 6.

Figure 6.

Body size and somatotropic hormones in nIGF1RKO mice. (a) Body length and (b) weight were increased in adult nIGF1RKO mutants. (c) Hypothalamic GHRH was highly expressed in mutants as compared with controls, whereas (d) SRIH was similar; a.u., arbitrary units. (e) Pituitary GH and (f) plasma IGF-I were strongly increased in adult nIGF1RKO mice. (g) Postnatal growth trajectories of nIGF1RKO and control groups diverge after 40 days of age; Number of individuals is indicated in each panel (n in panel g identical to panel b); Student’s t-test; Error bars, SEM.