Influence of pulse pressure on the dilation of isolated and pressurized mouse cerebral arteries induced by acetylcholine (Ach). Experiments were performed in the absence or presence of either (a) PEG-catalase (100 U/mL) or (b) gp91ds-tat (10 µM). Results are mean±SEM of n mice. *p < 0.05 compared to respective control condition; ‡p < 0.05 compared to static pressure conditions. ((a): Static n = 9 mice, Static + PEG-catalase n = 10 mice, PP n = 9 mice, PP + PEG-catalase n = 11 mice; (b) Static n = 9 mice, Static + gp91ds-tat n = 7 mice, PP n = 9 mice, PP + gp91ds-tat n = 6 mice).