Figure 5.
Influence of pulse pressure on the dilation of isolated and pressurized mouse cerebral arteries induced by acetylcholine (Ach). Experiments were performed in the absence or presence of either (a) PEG-catalase (100 U/mL) or (b) gp91ds-tat (10 µM). Results are mean±SEM of n mice. *p < 0.05 compared to respective control condition; ‡p < 0.05 compared to static pressure conditions. ((a): Static n = 9 mice, Static + PEG-catalase n = 10 mice, PP n = 9 mice, PP + PEG-catalase n = 11 mice; (b) Static n = 9 mice, Static + gp91ds-tat n = 7 mice, PP n = 9 mice, PP + gp91ds-tat n = 6 mice).