Figure 2.

Bland–Altman plot for midbrain (a), hippocampus (b), cerebellum (c), and occipital cortex (d) with different modeling methods to obtain striatal BP_ND. $\mathrm{Avg}B{P}_{\mathrm{ND}}=(B{P}_{\mathrm{ND},1}+B{P}_{\mathrm{ND},2})/2$, $\Delta =2\times 100\times (B{P}_{\mathrm{ND},1}-B{P}_{\mathrm{ND},2})/(B{P}_{\mathrm{ND},1}+B{P}_{\mathrm{ND},2})$, where BP_ND,1 was derived from 2TCM (black square), Logan plot (black cross), SRTM (red triangle), MRTM (green circle), and RLogan (blue diamond), and BP_ND,2 was always calculated from 2TCM. Each point represents the data of an individual animal (n = 6). BP_ND obtained from 2TCM and Logan plot was calculated from the V_T using the formula $B{P}_{\mathrm{ND}}=(V_T-V_{\mathrm{ND}})/V_{\mathrm{ND}}$.

2TCM: two-tissue compartment model; SRTM: simplified reference tissue model; MRTM: multilinear reference tissue model; RLogan: reference tissue Logan plot.