Table 1.
Shortlist of Candidate Genes Involved in Sexual Traits Decay in Asexual Leptopilina clavipes
| Mutation Type | Identified Using | Drosophila Homolog | Drosophila Tissue Enrichment | Nasonia Homolog | Nasonia Tissue Enrichment | Annotation | Notes |
|---|---|---|---|---|---|---|---|
| Enriched in reproductive tissue | |||||||
| Loss-of-function | snpEff | NP_648446.1 | Testis | XP_003425377.1 | Female body | Pleckstrin homology-like domain family B member 1 | Frame shift |
| Loss-of-function | snpEff | NP_001015401.1 | Testis | XP_003426117.1 | Testis | Tim17b | Stop codon removed |
| Loss-of-function | snpEff | NP_995777.1 | Testis | XP_008217920.1 | Testis | Ribonuclease H1 | Frameshift |
| Loss-of-function | snpEff | XP_008216187.1 | Testis | RNA-binding protein 4.1-like | Frameshift | ||
| Loss-of-function | snpEff | NP_610943.2 | Testis | XP_008206136.1 | Testis | Ubiquitin specific protease 20/33 | Frameshift |
| Non-tolerated | SIFT | NP_788479.1 | acc | XP_008207671.1 | Testis | ergic53 | validated |
| Non-tolerated | SIFT | NP_727442.1 | spt | XP_008217640.1 | Female body | Raspberry | |
| Non-tolerated | SIFT | NP_788565.1 | acc | XP_001602982.1 | Testis | Isoleucyl-tRNA synthetase | validated |
| Non-tolerated | SIFT | NP_611087.1 | Tubule | XP_001606432.1 | Testis | Cysteinyl-tRNA synthetase | |
| Non-tolerated | SIFT | NP_731238.1 | Testis | XP_008205904.1 | Testis | Dipeptidyl aminopeptidase III | Validated |
| Non-tolerated | SIFT | NP_608533.1 | Testis | XP_003427673.2 | Testis | Uncharacterized | Validated |
| Non-tolerated | SIFT | NP_649645.1 | acc | XP_001607849.1 | Testis | Small ribonucleoprotein particle protein SmD2 | |
| Non-tolerated | SIFT | NP_477412.1 | trachea | XP_001601436.1 | Testis | nop5 | |
| Non-tolerated | SIFT | NP_001261050.1 | XP_008205733.1 | Testis | Quaking related 54B | ||
| Unstable protein | MU-pro | NP_611131.2 | Fat body | XP_008208307.1 | Testis | Uncharacterized | |
| Unstable protein | MU-pro | NP_611350.1 | Tubule | XP_001067690.2 | Testis | Autophagy-related 7 | |
| Not enriched in reproductive tissue | |||||||
| Unstable protein | MU-pro | XP_008204426.1 | Female body | Uncharacterized | |||
| Unstable protein | MU-pro | ||||||
| Non-tolerated | SIFT | NP_611179.3 | XP_008203900.1 | Female body | Eps15 homology domain containing protein-binding protein 1 | ||
| Unstable protein | MU-pro | NP_611223.4 | Trachea | anaphase promoting complex subunit 10 | |||
| Non-tolerated | SIFT | NP_725570.1 | Fat body | XP_008208687.1 | Female head | HMG coenzyme A synthase | |
| Non-tolerated | SIFT | NP_572695.2 | Eye | XP_001604944.2 | Female body | antdh | |