Table 3. Univariate and multivariate analysis of overall survival in breast cancer patients.

Covariates	Univariate analysis		Multivariate analysis
HR (95%CI)	P	HR (95%CI)	P
Age at diagnosis
>35	1.000		1.000
≤35	1.263 (1.012–1.577)	0.039	1.489 (1.120–1.979)	0.006
Family history of breast cancer
No	1.000		—
Yes	0.738 (0.395–1.379)	0.341
Tumor size
T1	1.000		1.000
T2	2.609 (1.449–4.698)	0.001	1.662 (0.916–3.016)	0.095
T3	5.338 (2.939–9.695)	<0.001	2.517 (1.363–4.647)	0.003
T4	8.728 (4.814–15.822)	<0.001	4.208 (2.277–7.776)	<0.001
Node status
Negative	1.000		1.000
Positive	3.655 (2.883–4.633)	<0.001	4.339 (3.109–6.054)	<0.001
ER status
Negative	1.000		1.000
Positive	0.778 (0.642–0.943)	0.010	0.693 (0.552–0.871)	0.002