Table 2. Comparison of genotype and allele frequencies between the Mulao and Han populations [n (%)].
Mulao | Han | ||||
---|---|---|---|---|---|
SNP | Genotype/Allele | (n = 825) | (n = 781) | χ2 | P-value |
ZNF259 rs2075290 | AA/GA/GG | 413(50.1)/348(42.2)/64(7.7) | 460(58.9)/279(35.7)/42(5.4) | 13.494 | 0.001 |
A/G | 1174(71.2)/476(28.8) | 1199(76.8)/363(23.2) | 13.082 | 3 × 10−4 | |
ZNF259 rs964184 | CC/CG/GG | 467(56.6)/306(37.1)/52(6.3) | 515(65.9)/234(30.0)/32(4.1) | 15.514 | 4 × 10−4 |
C/G | 1240(75.2)/410(24.8) | 1264(80.9)/298(19.1) | 15.548 | 8 × 10−5 | |
BUD13 rs10790162 | GG/GA/AA | 472(57.2)/295(35.8)/58(7.0) | 519(66.5)/230(29.4)/32(4.1) | 16.595 | 2 × 10−4 |
G/A | 1239 (75.1)/411 (24.9) | 1268 (81.2)/294 (18.8) | 17.355 | 3 × 10−5 | |
BUD13 rs17119975 | AA/AG/GG | 537(65.1)/254(30.8)/34(4.1) | 472(60.4)/284(36.4)/25(3.2) | 6.032 | 0.049 |
A/G | 1328 (80.5)/322 (19.5) | 1228 (78.6)/334 (21.4) | 1.722 | 0.189 | |
BUD13 rs11556024 | CC/CT/TT | 700(84.9)/120(14.5)/5(0.6) | 671(85.9)/103(13.2)/7(0.9) | 1.038 | 0.595 |
C/T | 1520 (92.1)/130 (7.9) | 1445 (92.5)/117 (7.5) | 0.171 | 0.680 | |
MLXIPL rs799161 | CC/CT/TT | 361(43.8)/390(47.2)/74(9.0) | 345(44.2)/378(48.4)/58(7.4) | 1.285 | 0.526 |
C/T | 1112 (67.4)/538 (32.6) | 1068 (68.4)/494 (31.6) | 0.353 | 0.552 | |
MLXIPL rs35332062 | CC/CT/TT | 717(86.9)/98(11.9)/10(1.2) | 692(88.6)/83(10.6)/6(0.8) | 1.482 | 0.477 |
C/T | 1532 (92.8)/118 (7.2) | 1467 (93.9)/95 (6.1) | 1.483 | 0.223 | |
MLXIPL rs3812316 | CC/CG/GG | 751(91.0)/67(8.1)/7(0.9) | 703(90.0)/76(9.7)/2(0.3) | 3.726 | 0.155 |
C/G | 1569 (95.1)/81 (4.9) | 1482 (94.9)/80 (5.1) | 0.076 | 0.783 | |
MLXIPL rs13235543 | CC/CT/TT | 704(85.3)/114(13.8)/7(0.9) | 682(87.3)/94(12.0)/5(0.7) | 1.401 | 0.496 |
C/T | 1522 (92.2)/128 (7.8) | 1458 (93.3)/104 (6.7) | 1.447 | 0.229 |
ZNF259, zinc finger protein 259; BUD13, BUD13 homolog; MLXIPL, MLX interacting protein-like.