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. 2014 Jul 3;4:5565. doi: 10.1038/srep05565

Table 5. Correlation between the genotypes of the MLXIPL, BUD13 and ZNF259 SNPs and serum lipid levels in the Mulao and Han populations.

Lipid SNP Affected allele/Other allele Affected genotype/Other genotype Beta Std. error t P-value
Mulao plus Han              
TC BUD13 rs10790162   AA, GA/GG 0.167 0.049 3.407 0.001
TG BUD13 rs10790162 A/G   0.248 0.048 5.163 <1 × 10−7
LDL-C BUD13 rs17119975 G/A   0.513 0.183 2.800 0.005
  BUD13 rs10790162 A/G   0.099 0.039 2.546 0.011
  BUD13 rs13235543 T/C   0.149 0.069 2.164 0.031
ApoA1 BUD13 rs13235543   TT, CT/CC 0.097 0.031 3.093 0.002
  BUD13 rs11556024 T/C   0.060 0.027 2.234 0.025
ApoB BUD13 rs13235543   TT, CT/CC 0.097 0.031 3.093 0.002
  BUD13 rs10790162 A/G   0.058 0.024 2.405 0.016
ApoA1/ApoB BUD13 rs10790162   AA, GA/GG −0.083 0.030 −2.754 0.006
  BUD13 rs11556024 T/C   0.133 0.051 2.611 0.009
  BUD13 rs13235543 T/C   −0.113 0.053 −2.138 0.033
Mulao              
TC BUD13 rs10790162   AA, GA/GG 0.200 0.071 2.836 0.005
TG BUD13 rs10790162   AA, AG/GG 0.292 0.062 4.744 2 × 10−5
  BUD13 rs13235543   TT, CT/CC 0.248 0.101 2.450 0.015
  ZNF259 rs964184   GG, CG/CC −0.401 0.192 −2.083 0.037
LDL-C BUD13 rs10790162 A/G   0.167 0.067 2.485 0.013
ApoA1 MLXIPL rs35332062   TT, CT/CC 0.510 0.155 3.284 0.001
  MLXIPL rs35332062 T/C   −0.427 0.179 −2.392 0.017
ApoB BUD13 rs13235543   TT, CT/CC 0.214 0.059 3.608 4 × 10−4
ApoA1/ApoB BUD13 rs13235543 T/C   −0.180 0.090 −1.999 0.046
  BUD13 rs10790162 A/G   −0.124 0.063 −1.978 0.048
Han              
TC MLXIPL rs799161 T/C   0.127 0.062 2.042 0.042
TG BUD13 rs17119975 G/A   0.308 0.081 3.826 1 × 10−4
  BUD13 rs10790162 A/G   0.268 0.083 3.211 0.001
  BUD13 rs17119975   GG, AG/AA −0.561 0.240 −2.340 0.020
HDL-C MLXIPL rs35332062 T/C   0.788 0.127 6.218 <1 × 10−7
  BUD13 rs13235543 T/C   −0.407 0.116 −3.501 5 × 10−4
  BUD13 rs11556024   TT, CT/CC 0.175 0.061 2.852 0.004
  MLXIPL rs3812316   GG, CG/CC −0.329 0.126 −2.614 0.009
LDL-C MLXIPL rs799161 T/C   0.196 0.066 2.990 0.003
ApoA1 BUD13 rs11556024 T/C   0.095 0.028 3.465 0.001
ApoB BUD13 rs10790162 A/G   0.055 0.017 3.198 0.001
  ZNF259 rs2075290   GG, AG/AA −0.048 0.020 −2.396 0.017
  BUD13 rs11556024   TT, CT/CC −0.039 0.019 −2.018 0.044
ApoA1/ApoB BUD13 rs11556024   TT, CT/CC 0.182 0.050 3.642 2 × 10−4
  BUD13 rs10790162   AA, GA/GG −0.091 0.031 −2.974 0.003
  MLXIPL rs799161 T/C   −0.107 0.036 −2.999 0.003

Multivariable linear regression analyses with stepwise modeling were performed to assess the correlation between serum lipid levels and genotypes in Mulao, Han, and combined the Mulao and Han populations.