Table 1.
Top Genes Expressed Differentially by Microbiota Treatment
| Ensembl Gene ID | Gene Description | Direction of Diff. Expr. | Fold Change |
|---|---|---|---|
| ENSGACG00000008429 | myeloperoxidase-like protein* | CV-enriched | 5.35 |
| ENSGACG00000010234 | cathepsin Bb | CV-enriched | 3.99 |
| ENSGACG00000017166 | myeloid-specific peroxidase | CV-enriched | 3.52 |
| ENSGACG00000011676 | BPI fold containing family C | CV-enriched | 3.47 |
| ENSGACG00000006045 | zymogen granule protein 16B | CV-enriched | 3.23 |
| ENSGACG00000006706 | tumor necrosis factor receptor superfamily, member 11b | CV-enriched | 2.99 |
| ENSGACG00000010404 | interleukin 22 receptor, alpha 2 | CV-enriched | 2.65 |
| ENSGACG00000010912 | deleted in malignant brain tumors 1 protein* | CV-enriched | 2.18 |
| ENSGACG00000001729 | interleukin 8* | CV-enriched | 2.13 |
| ENSGACG00000014415 | low choriolytic enzyme precursor* | CV-enriched | 2.11 |
| ENSGACG00000001881 | leukocyte elastase inhibitor* | GF-enriched | 1.67 |
| ENSGACG00000014112 | developing brain homeobox 1 | GF-enriched | 1.65 |
| ENSGACG00000012888 | heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 2 | GF-enriched | 1.50 |
| ENSGACG00000006375 | serpin peptidase inhibitor, clade H (heat shock protein 47), member 1b | GF-enriched | 1.47 |
| ENSGACG00000014099 | mucin 5f | GF-enriched | 1.34 |
| ENSGACG00000020294 | V-set and immunoglobulin domain containing 1 | GF-enriched | 1.33 |
| ENSGACG00000018013 | protease, serine, 12 (neurotrypsin, motopsin) | GF-enriched | 1.31 |
| ENSGACG00000010026 | ankyrin repeat and death domain containing 1B | GF-enriched | 1.28 |
| ENSGACG00000008795 | inositol-trisphosphate 3-kinase A | GF-enriched | 1.25 |
| ENSGACG00000011569 | transient receptor potential cation channel, subfamily M, member 6 | GF-enriched | 1.24 |
Note.—Ten top-ranked (by fold change) conventional-enriched and germ-free-enriched stickleback genes, of 72 total differentially expressed. In cases where no Ensembl gene description was available (marked by an asterisk), descriptions were obtained from top BLASTp hits of searches against the NCBI nr database.