Table 5.
Nonsynonymous SNPs in mce1–4 operons
| Operon | Number of nsSNPs |
|||
|---|---|---|---|---|
| Total | Lineage-Specific | Specific to Small Groups |
||
| Total | Affected | |||
| mce1 | 48 | 11 (22%) | 37 | 10 (27%) |
| mce2 | 35 | 5 (14%) | 30 | 15 (50%) |
| mce3 | 32 | 8 (25%) | 24 | 12 (50%) |
| mce4 | 26 | 2 (8%) | 24 | 15 (63%) |
Note.—A total number of nsSNPs in mce genes was counted. All identified mutations were divided into two groups: specific to an established lineage and located in small groups of at least two isolates. Number of affected mutations was counted using PredictSNP. Note that mce4 operon has the biggest (63%) and mce1—the smallest (27%) percent of small group mutations possibly affecting protein function. Full version of the table with descriptions of SNPs and groups is listed in supplementary material S2, Supplementary Material online.