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. 2015 Apr 1;5:9513. doi: 10.1038/srep09513

Figure 2. MSD induced changes in neurogenesis in hippocampus of young offspring and impact of minocycline administration.

Figure 2

(a) Representative images of BrdU and DCX labeled cells in the DG of hippocampus, arrow represent the merged images. The total number of BrdU+ cells (b), the number of BrdU+/DCX+ cells (c) and the percentage of BrdU+/DCX+ out of all BrdU+ cells (d) were reduced in the MSD young offspring rats. After minocycline treatment, the total number of BrdU+ cells, the number of BrdU+/DCX+ cells and the percentage of BrdU+/DCX+ out of all BrdU+ cells were increased. Representative figures of the volumes of DG (e) and the GCL areas (f). (g) The volume of DG was not altered in young offspring rats. (h) MSD-mino did not change the volume of GCL subregion in young offspring. * P < 0.05, ** P < 0.01 vs. the control-saline. # P < 0.05, # # P < 0.01 vs. the MSD-saline. Values are the mean ± SEM. Scale bars: A: 20 μm; E, F: 10 μm.