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. 2015 Apr 10;5:9618. doi: 10.1038/srep09618

Figure 1. Schematic representation of glucose (Glc) metabolism and the central position of UDP-glucose (UDP-Glc) in cellular pathways.

Figure 1

UDP-glucose pyrophosphorylase (UGP, highlighted by green sphere) catalyzes the interconversion of glucose-1-phosphate (Glc-1-P) and uridine triphosphate (UTP) to inorganic pyrophosphate (PPi) and UDP-glucose (UDP-Glc). GK/HK: gluco-/hexokinase, G6PC: glucose-6-phosphatase, PGM: phosphoglucomutase, GYS: glycogen synthase, PYG: glycogen phosphorylase, UGGT: UDP-glucose:glycoprotein transferase, UGDH: UDP-glucose 6-dehydrogenase, UGT: UDP-glucuronyltransferase, GALE: UDP-glucose-4-epimerase, GALT: galactose-1-phosphat-uridylyltransferase, GK: galactokinase, LS: lactose synthase, LCT: lactase, Glc-6-P: glucose-6-phosphate, UDP-GlcA: UDP-glucuronic acid, Gal: galactose, Gal-1-P: galactose-1-phosphate, UDP-Gal: UDP-galactose.