Table 1. Identification of the kinetic parameters that characterize the ITUD system. We determined the kinetic parameters that discriminate the output of the ITUD system from those of the alternative systems when a small perturbation was given. The ratio of the sensitivities were obtained using a positive (+1%) and a negative (−1%) perturbation. The five parameters (ID: 11–15) displayed noticeable differences (<20% vs. >60% of the others).

ID	Parameter	Perturbation
		Positive (+1%)		Negative (−1%)
I/S (%)	I/D (%)	I/S (%)	I/D (%)
1	βT	60.42	100	60.42	100
2	αT	60.48	100	60.37	100
3	kST	60.26	100	60.59	100
4	Km_ST	60.48	100	60.37	100
5	kE3T	60.57	100	60.28	100
6	Km_E3T	60.37	100	60.47	100
7	Vm_ubT	60.39	100	60.46	100
8	Km_ubT	60.43	100	60.41	100
9	Vm_pro	60.43	100	60.42	100
10	Km_pro	60.42	100	60.42	100
11	βE3	10.78	17.85	10.76	17.80
12	αE3	9.43	15.65	12.07	19.92
13	βTE3	12.04	19.88	9.43	15.65
14	KTE3	10.43	17.28	11.10	18.36
15	nTE3	10.99	18.18	10.54	17.46
16	βP	100	100	100	100
17	αP	100	100	100	100
18	βTE3P	100	100	100	100
19	KTP	100	100	100	100
20	nTP	100	100	100	100

I, S, and D: The sensitivity of ITUD, SNFL, and DTUD, respectively.