Table 2. The eGFR annual decline rate by subgroups.

Subgroup	Reference group	N	Annual eGFR decline (ml/min1.73 m2 per year)	p-value	Age-adjusted annual eGFR decline (ml/min1.73 m2 per year)	p-value
Age	Age<60 years	1010	3.11 (0.41)	0.003	4.20 (0.59)	0.9
	Age≥60 years	3619	1.75 (0.21)		4.25 (1.00)
Sex	Female	1960	2.18 (0.29)	0.51	4.37 (0.62)	0.45
	Male	2640	1.94 (0.25)		4.08 (0.60)
DMN	No	2835	0.85 (0.24)	<0.001	3.14 (0.59)	<0.001
	Yes	1765	3.96 (0.30)		6.31 (0.63)
Hypertension	No	918	1.51 (0.42)	0.16	3.62 (0.67)	0.094
	Yes	3682	2.17 (0.21)		4.41 (0.59)
CVD	No	4094	2.02 (0.20)	0.8	4.19 (0.58)	0.5
	Yes	506	2.19 (0.57)		4.61 (0.83)
Proteinuria	No	1953	0.36 (0.29)	<0.001	2.01 (0.65)	<0.001
	Yes	2676	3.28 (0.25)		4.77 (0.58)
Dyslipidemia	No	4203	2.05 (0.67)	0.9	4.24 (0.59)	0.7
	Yes	397	2.00 (0.64)		3.95 (0.81)

Abbreviations: DMN: Diabetic Nephropathy; CVD: Cardiovascular disease