Table 2. SNP ID, nucleotide and Amino Acid changes, number of individuals and population frequency of each mutation.

SNP ID	Nucleotide change	Amino Acid change	Total individuals	N°/ Freq AFR	N°/ Freq AMR	N°/ Freq EAS	N°/Freq EUR	N°/ Freq SAS	Total Allele Frequency
rs36020563	G/A	His144His	1	1 (0.0008)	0	0	0	0	0.00019
rs113082294	C/G	Val134Val	9	0	2 (0.0029)	0	7 (0.007)	0	0.00179
rs111645889	G/A	Ala130Val	1	1 (0.0008)	0	0	0	0	0.00019
rs33971634	G/A	Gln128	1	0	1 (0.0014)	0	0	0	0.00019
rs33946267	C/G	Glu122Gln	3	0	0	0	0	3 (0.0031)	0.00059
rs33958637	T/G	Asn109His	1	0	0	1 (0.001)	0	0	0.00019
rs193922562	G/A	Gly108Gly	1	1 (0.0008)	0	0	0	0	0.00019
rs145669504	G/T	Leu82Leu	5	0	0	5 (0.005)	0	0	0.00099
rs281864900	CAAAG/C	Phe42fs	5	0	0	5 (0.005)	0	0	0.00099
rs11549407	G/A	Gln40	1	0	1 (0.0014)	0	0	0	0.00019
rs1135071	C/A	Arg31Ser	1	0	0	0	1 (0.001)	0	0.00019
rs33943001	C/G	#	1	0	0	0	0	1 (0.001)	0.00019
rs33971440	C/T	#	1	0	1 (0.0014)	0	0	0	0.00019
rs35578002	G/T	Glu30Gly	1	1 (0.0008)	0	0	0	0	0.00019
rs33950507	C/T	Glu27Lys	14	0	0	8 (0.0079)	0	6 (0.0061)	0.00279
rs33986703	T/A	Lys18	6	0	0	6 (0.006)	0	0	0.00119
rs63750783	C/T	Trp16	2	0	0	0	0	2 (0.002)	0.00039
rs334	T/A	Glu7Val	137	132 (0.0072)	5 (0.0998)	0	0	0	0.02735
rs33930165	C/T	Glu7Lys	17	17 (0.0129)	0	0	0	0	0.00339
rs33912272	G/A	Pro6Ser	1	0	0	0	1 (0.001)	0	0.00019

AFR: African.; AMR: American; EAS: Eastern Asian; EUR: European; SAS: Southern Asian.