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. 2017 Apr 5;12(4):e0175034. doi: 10.1371/journal.pone.0175034

Table 1. Immunopathological data obtained from the experimental study.

Number (%) of animals showing CVPC, mean Ph. Eur. Score (± SD), mean S/P ratio (± SD) and number (%) of seropositive (IgG) and positive animals to M. hyopneumoniae-IgG1 and IgG2 in sera and to IgG and IgA antibodies in BALF at 21 and 28 dpi. Different superscripts within a column indicate significant differences among days post-inoculation (p<0.05).

Lung pathology Serology Sera isotypes detection BALF antibodies detection
Days post-inoculation (dpi) No. of animals with CVPC (%) Mean Ph. Eur. Score (± SD) No. of seropositive animals (%) Mean S/P ratio (± SD) No. of IgG1 positive animals (%) No. of IgG2 positive animals (%) No. IgG positive animals (%) No. of IgA positive animals (%)
21 (n = 37) 30 (81.1)a 7.7 (± 8.1)a 3 (8.1)a 0.09 (± 0.22)a 0 (0)a 0 (0)a 34 (91.9)a 36 (97.3)a
28 (n = 60) 48 (80)a 9.5 (± 10.3)a 12 (20)a 0.26 (± 0.34)b 18 (30)b 32 (53)b 37 (61.7)b 45 (75)b