Table 5.
Regions associated with differential fMRI BOLD response to milkshake taste in Behavioral weight loss compared to control from baseline to 12-weeks (N = 34)
| Hemi | Peak | Peak | Peak | Peak | |||||
|---|---|---|---|---|---|---|---|---|---|
| sphere e |
k | Z | T | p(FWE- corr) |
p(unc) | xa | y | z | |
| BWL baseline > Control at baselineb | |||||||||
| Caudate | R | 4 | 3.8 | 4.04 | 0.001 | 7.36E-05 | 21 | 11 | 20 |
| BWL baseline > BWL at 12 weeksb | |||||||||
| Medial prefrontal cortex | R | 6 | 4.49 | 4.90 | 0.0001 | 3.61E-06 | 24 | 14 | 18 |
| Caudate | R | 1 | 3.34 | 3.51 | <0.01 | 0.0004 | 21 | 11 | 20 |
| Central sulcus | R | 6 | 3.89 | 4.16 | 0.001 | 4.99E-05 | 33 | −19 | 28 |
| Control at 12 weeks > BWL at 12 weeksb | |||||||||
| Orbitofrontal Cortex | R | 6 | 3.95 | 4.23 | 0.001 | 3.92E-05 | 24 | 35 | 5 |
Threshold: where p < .01 FWE-corrected.
R = right, L = left;
k = cluster size in voxels
We used WFUPickAtlas within Xjview (http://www.alivelearn.net/xjview) for neuroanatomical labelling.
Peak Z = Z value of the peak of the cluster
Peak T = T value of the cluster peak
Peak p (FWE-corr) = Family-wise error rate corrected p value
Peak p (unc) = Peak p (uncorrected)
x, y, z coordinates are in Montreal Neurological Institute space.
The direction of change from baseline to 12 weeks in fMRI BOLD response to milkshake taste vs crosshairs in the regions associated with differential change between the BWL and control groups.