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. Author manuscript; available in PMC: 2018 Jan 1.
Published in final edited form as: Radiat Res. 2016 Dec 21;187(1):79–88. doi: 10.1667/RR14358.1

FIG. 4.

FIG. 4

Percentage change versus time in the MRI vascular parameters after combined Cilengitide and radiation treatments in the tumor region of interest. Cilengitide was administered 1 (panel A) or 8 h (panel B) before irradiation. The pattern of response in the 1 h group resembles that of irradiation alone [see fig. 2 in ref. (7)], while the pattern of response in the 8 h group shows a preservation of the vascular parameters starting at 4 h postirradiation and indicates a synergistic effect. *P < 0.05. from pretreatment levels (P = 0.043), followed by an increase to near pretreatment values at 4 h postirradiation (P