Table 1.
Vaping behavior and nicotine pharmacokinetics during 90 minutes of ad libitum access to electronic cigarettes
| Participant | Brand | Nicotine concentration in e-liquid (ug/mg) | Number of puffs in 90minutes | Average puff duration (s) | Average interpuff interval (s) | Amount of e-liquid used (mg) | Nicotine inhaled (mg) | Tmax (min) | Cmax (ng/mL) | AUC0→90 (ng/mL min) |
|---|---|---|---|---|---|---|---|---|---|---|
| A. Tank e-cigarettes | ||||||||||
| 1 | Kanger EVOD2 | 15.3 | 37 | 3.2 | 139 | 166 | 2.5 | 75 | 11.0 | 591 |
| 3 | Kanger T3D | 11.4 | 84 | 2.7 | 57 | 309 | 3.5 | 60 | 10.8 | 568 |
| 5 | Kanger T3D | 15.3 | 123 | 2.0 | 41 | 255 | 3.9 | 90 | 12.6 | 834 |
| 6 | Kanger EVOD | 8.6 | 82 | 3.2 | 60 | 237 | 2.0 | 90 | 9.5 | 608 |
| 7 | Kanger Aerotank V2 | 12.1 | 121 | 2.3 | 43 | 644 | 7.8 | 90 | 18.6 | 1144 |
| 10 | Kanger EVOD | 5.6 | 26 | 5.9 | 181 | 171 | 1.0 | 60 | 2.9 | 200 |
| 12 | Vapor4Life | 5.9 | 98 | 4.3 | 50 | 548 | 3.2 | 60 | 11.5 | 750 |
| 13 | Kanger Protank II | 5.7 | 71 | 1.7 | 74 | 374 | 2.1 | 30 | 6.8 | 457 |
| B. Cartridge e-cigarettes | ||||||||||
| 2 | V2 Cigs Red 18 | 13.9 | 60 | 6.6 | 84 | 258 | 3.6 | 90 | 12.5 | 656 |
| 9 | Blu E-cigarette | 12.6 | 10 | 3.9 | 554 | 29 | 0.4 | 90 | 1.6 | 65 |
| C. Rebuildable atomizers (RBAs) | ||||||||||
| 4 | Vulcan | 5.7 | 33 | 3.2 | 168 | 1349 | 7.7 | 90 | 29.0 | 1669 |
| 8 | K101 | 5.0 | 10 | 3.9 | 7 | 376 | 1.9 | 15 | 10.0 | 603 |
| 11 | Nimbus | 5.0 | 71 | 2.6 | 71 | 2373 | 12.0 | 90 | 29.7 | 1574 |
|
| ||||||||||
| Mean | 9.4 | 64 | 3.5 | 118 | 545 | 4.0 | 71.5 | 12.8 | 748 | |
| Median | 8.6 | 71 | 3.2 | 71 | 309 | 3.2 | 90 | 11.0 | 608 | |
| SD | 4.1 | 38 | 1.4 | 141 | 641 | 3.3 | 25.4 | 8.5 | 470 | |
| Q1 | 5.7 | 33 | 2.6 | 50 | 237 | 2.0 | 60 | 9.5 | 568 | |
| Q3 | 12.6 | 84 | 3.9 | 139 | 548 | 3.9 | 90 | 12.6 | 834 | |
Note: Subject IDs correspond to subject IDs in a previously published study (reference 6); Tmax, time to maximum plasma nicotine concentration; Cmax, maximum plasma nicotine concentration; AUC0→90, area under the plasma nicotine concentration time curve from 0 to 90 minutes; SD, standard deviation; Q1 is the first quartile; Q3 is the third quartile.