Table 1.

Overview of Intervention Sessions

Sessions	Time point	Components	Main goals	Worksheet(s)
Session 1	Week 1	Introduction, assessment, education, and dosing scheduling	Build rapport, provide key PrEP information, set client's dosing schedule.	Pros and Cons of Adherence vs. Nonadherence
Session 2	Week 2	Focus on adherence and motivational interviewing techniques	Identify motivation around adherence, problem solving barriers to adherence.	Problem-Solving Worksheet
Session 3	Week 3	Follow up on adherence and focus on sexual risk behavior	Assess client's sexual risk behavior and build knowledge around sexual safety.	Sexual Comfort Zone and Pros/Cons to Condoms added to PrEP vs. PrEP alone worksheets
Session 4	Week 4	Follow up on adherence and optional mini-module (as needed)	Review previous topics, conduct an optional module.	See Optional Modules
Optional Module 1	Week 4	Mental health and breathing retraining (if needed)	Identify links between mental health symptoms and health behaviors.	Problem-Solving Worksheet
Optional Module 2	Week 4	Substance abuse counseling messages	Increase motivation to alter substance use patterns, harm reduction.	Substance Use Worksheet
Booster Sessions	Months 2 and 3	Follow up on adherence and content review	Specific content revisited is tailored to each client.	Previous worksheet(s) as needed