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. 2017 Mar 14;23(1):80–86. doi: 10.3350/cmh.2016.0034

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Copyright © 2017 by The Korean Association for the Study of the Liver

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 2. — The tumor was well-circumscribed along the edge of the tumor but focal foci of infiltrative growth into the surrounding non-tumorous liver parenchyme were seen in the immunostaining of HMB45 (×40) (A). The tumor mainly composed of epithelioid cells and arranged in trabecular growth pattern (×100) (B). The epithelioid tumor cells had abundant granular eosinophilic cytoplasm, distinct cell border, eccentrically located round nuclei with small nucleoli, and foci of mild to moderate nuclear atypism (×200) (C). Extramedullary hematopoiesis was recognized in the sinusoidal spaces between the tumor cells (×200) (D). The surrounding non-tumorous liver parenchyme showed chronic hepatitis with early cirrhotic change (Masson trichrome stain, E) and foci of lymphoid aggregate in some portal tracts (×100) (F).