Table 2.
Improvement of menorrhagia after high-intensity focused ultrasound for adenomyosis
| Study | Reduction in menorrhagia (%)a) |
|||||
|---|---|---|---|---|---|---|
| 1 | 3 | 6 | 12 | 18 | 24 | |
| Magnetic resonance-guided | ||||||
| Ferrari et al. [18], 2016 | - | - | - | 66.4 | - | - |
| Fan et al. [11], 2012 | 12.4 | 25.3 | 16.4 | 24.9 | - | - |
| Polina et al. [19], 2012 | - | 31.6 | 47.4 | - | - | - |
| Kim et al. [20], 2011 | - | 25.9 | 40.7 | - | - | - |
| Fukunishi et al. [12], 2008 | 33.3 | 53.5 | 44.8 | - | - | - |
| Ultrasound-guided | ||||||
| Lee et al. [17], 2015 | - | 55.6 | 52.4 | 58 | - | - |
| Shui et al. [21], 2015 | - | 44.8b) | - | 48.3b) | - | 44.8b) |
| Long et al. [14], 2015 | - | 32.9 | 50.4 | 64.7 | - | - |
| Zhou et al. [15], 2011 | - | 48.0b) | - | - | 44.0b) | - |
| Wang et al. [16], 2009 | - | 57.0-80.8b, c) | - | - | - | |
a)
Months after treatment, based on the symptom severity score of the Uterine Fibroid Symptom and Quality of Life questionnaire, unless otherwise specified.
b)
Based on menstrual volume/menorrhagia score.
c)
Varied depending on power output (290-420 W).