Table 5.
Treatment data
| Study | Treatment timea) | Sonication timeb) | Total exposure energy (J) | Volume of uterus (cm3) | Volume of adenomyotic lesion (cm3) |
|---|---|---|---|---|---|
| Magnetic resonance-guided | |||||
| Fan et al. [11], 2012 | 114±48 (42-192) | 990.5±480.6 (245.0-1,727.0) | 299,019.5±154,636.0 | 272.0±99.2 (148.8-440.0) | 94.9±54.6 (30.4-208.4) |
| Polina et al. [19], 2012 | 110 | NA | 108,996 | NA | 91 |
| Kim et al. [20], 2011 | 150±40 | NA | NA | 430±230 | NA |
| Fukunishi et al. [12], 2008 | <180 | NA | 157,745.4c) (69,066.8-491,840.3) | 445±296 (95% CI, 307-584) | NA |
| Ultrasound-guided | |||||
| Liu et al. [13], 2016 | 64c) (IQR, 47-91) | 1,135c) (IQR, 769-1,561) | NA | 274.4±174.8 (47-1,390) | 70.7±33.0 (16-177) |
| Lee et al. [17], 2015 | 82.3c) | 1,049.4c) | 363,556.6c) | 264.1c) | NA |
| Shui et al. [21], 2015 | 103.8±59.4 (11.0-247.0) | 1,197.3±744.2 (114-4,000) | 454,016.2±282,200.6 (43,228.8-1,516,800) | 253.1±109.3 (100.4-708.2) | 66.2±48.6 (4.2-373.3) |
| Zhou et al. [15], 2011 | <180 | NAd) | NAd) | NAd) | NA |
| Wang et al. [16], 2009 | NA | (468-3,413) | (138,000-1,432,000) | NA | NA |
Values are presented as mean±standard deviation (range), unless otherwise specified.
NA, not available; CI, confidence interval; IQR, interquartile range.
a)
Treatment time (in minutes) was defined as the time from the first sonication to the last sonication, except in the study by Fan et al. [11], in which it was defined as the time from the first magnetic resonance localization scan to the last sonication.
b)
Sonication time (in seconds) was defined as the time of ablation when energy was delivered to the target.
c)
Median value.
d)
Mean treatment time between 1,132 and 1,820 seconds, mean total exposure energy between 384,637 and 765,571 J, and mean uterine volume between 213 and 253 cm3; varied depending on power output (290-420 W).