Table 1. Characteristics of identified studies.

						Key results/Findings (psychometric properties)
Author (s)	Country	Year	Sample Size	Source		PWB α	EWB α	FGWB α	SWB α	CF α	FAHI	Established	Sensitivity
											Total α	validity	to change
Byrne S. & Petry N. [30]	USA	2012	n = 170	Single		0.85	0.89	0.82	0.70	0.70	0.92	Convergent	YES
												Discriminant
Peterman A.H. et al [22]	USA	1997	n = 361	BIOQoL (n = 110)	$\begin{array}{l}\\ \\ \end{array}\}$							Divergent	YES
				VCU data (n = 39)		0.91	0.82	0.86	0.73	0.75	0.91	Construct
				Multi-center trial (n = 212)
Viala-Danten M. et al [13]	USA	2010	n = 1661	POWER trial (n = 565)		0.91	0.83	0.89	0.85	0.75	NR	Construct	NR
				DUET trial (n = 1,091*)		0.92	0.84	0.89	0.84	0.72	NR
Cella D.F. et al [17]	USA	1996	n = 245	Stress sample (n = 110)	$\begin{array}{l}\\ \\ \end{array}\}$						0.91	Concurrent	YES
				BIOQoL English (n = 71)		NR	NR	NR	NR	NR	0.91
				BIOQoL Spanish (n = 64)							0.92
Feinberg J. et al [34]	USA, Canada	2011	n = 429	Single		NR	NR	NR	NR	NR	NR	NR	NR
	& Puerto Rico
Earthman C.P. [33]	USA	2002	n = 25	Single		0.91 (7 Item)	NR	NR	NR	NR	NR	NR	NR
Hasanah C.I., Zaliha A.R.,	Malaysia	2010	n = 271	Single		NR	NR	NR	NR	NR	NR	NR	NR
Mahiran M. [23]
Cianfrocca M. et al [35]	USA	2010	n = 73	Single		NR	NR	NR	NR	NR	NR	NR	NR
Rao D. et al [24]	Continental	2007	n = 273	Single		NR	NR	NR	NR	NR	NR	NR	NR
	United States
	& Puerto rico
Abrams D.I, Steinhart C.,	USA	2000	n = 221	Single		NR	NR	NR	NR	NR	NR	NR	NR
Frascino R. [36]
Tomita A et al [31]	South Africa	2013	n = 160	Single		0.88	0.83	0.85	0.72	0.65	0.86	NR	NR
Tomita A et al [37]	South Africa	2014	n = 51	Single		0.92	0.80	0.83	0.73	0.60	0.90	NR	NR
Diamond C.,	USA	2010	n = 100	Single		NR	NR	NR	NR	NR	NR	NR	NR
Taylor T.H.,
Anton-Culver H. [38]
Cella D.F. et al [39]	USA	2010	n = 1203	DUET– 1 (n = 612)		NR	NR	NR	NR	NR	NR	NR	NR
				DUET– 2 (n = 591)
Sikkema K.J. et al [40]	USA	2005	n = 235	Single		NR	NR	NR	NR	NR	NR	NR	NR
Winston A. [41]	Multi- centered	2010	n = 256	Single		NR	NR	NR	NR	NR	NR	NR	NR

BIOQoL-Bilingual Intercultural Oncology Quality of Life, VCU -Virginia Commonwealth University, FAHI–Functional Assessment of HIV infection, PWB–Physical Wellbeing, EWB–Emotional Wellbeing, FWB–Functional and Global Wellbeing, SWB–Social Wellbeing, CF–Cognitive Functioning, POWER–Performance Of TMC114/r When evaluated in treatment-Experienced patients with protease inhibitor Resistance. DUET- a randomized, double-blind, placebo-controlled, phase III trial examining the efficacy, tolerability, and safety of TMC125 in treatment-experienced patients. NR–Not Reported

* Number of patients with all sub scale scores available