Table 2. Comparison of regional hemodynamic responses of suicide attempters, non-attempters, and healthy control subjects threshold of p < 0.00096.
MINI coordinates | Mean oxy-Hb changes | |||||||||
---|---|---|---|---|---|---|---|---|---|---|
Estimated area | R/L | NIRS channel | x | y | z | SAs | NAs | HCs | F value | Post hoc |
Middle frontal gyrus | L | 8 | −46 | 23 | 44 | 0.013 ± 0.068 | 0.039 ± 0.077 | 0.113 ± 0.118 | 11.2 | SA < HC, NA < HC |
L | 18 | −42 | 42 | 32 | 0.038 ± 0.072 | 0.038 ± 0.067 | 0.125 ± 0.111 | 12.3 | SA < HC, NA < HC | |
L | 19 | −55 | 18 | 31 | 0.035 ± 0.067 | 0.072 ± 0.066 | 0.160 ± 0.113 | 19.3 | SA < HC, NA < HC | |
L | 28 | −35 | 58 | 20 | 0.046 ± 0.072 | 0.053 ± 0.081 | 0.126 ± 0.127 | 7.5 | SA < HC, NA < HC | |
L | 49 | −35 | 63 | −4 | 0.072 ± 0.071 | 0.097 ± 0.109 | 0.194 ± 0.143 | 11.4 | SA < HC, NA < HC | |
Inferior frontal gyrus | R | 34 | 59 | 27 | 8 | 0.065 ± 0.096 | 0.092 ± 0.104 | 0.198 ± 0.128 | 13.5 | SA < HC, NA < HC |
R | 45 | 53 | 43 | −6 | 0.093 ± 0.100 | 0.108 ± 0.094 | 0.194 ± 0.148 | 7.7 | SA < HC, NA < HC | |
L | 29 | −52 | 36 | 19 | 0.065 ± 0.083 | 0.076 ± 0.070 | 0.172 ± 0.121 | 13.7 | SA < HC, NA < HC | |
L | 39 | −44 | 53 | 6 | 0.064 ± 0.075 | 0.084 ± 0.086 | 0.217 ± 0.144 | 21.2 | SA < HC, NA < HC | |
L | 40 | −57 | 28 | 7 | 0.076 ± 0.113 | 0.091 ± 0.096 | 0.202 ± 0.164 | 9.2 | SA < HC, NA < HC | |
L | 50 | −51 | 45 | −6 | 0.066 ± 0.132 | 0.088 ± 0.094 | 0.247 ± 0.174 | 18.0 | SA < HC, NA < HC | |
Precentral gyrus | R | 23 | 64 | 8 | 20 | 0.025 ± 0.120 | 0.049 ± 0.109 | 0.171 ± 0.136 | 12.2 | SA < HC, NA < HC |
L | 9 | −57 | −1 | 43 | −0.011 ± 0.094 | 0.073 ± 0.087 | 0.107 ± 0.116 | 11.4 | SA < NA, SA < HC | |
L | 30 | −62 | 10 | 20 | 0.008 ± 0.101 | 0.063 ± 0.073 | 0.119 ± 0.139 | 7.8 | SA < HC | |
Postcentral gyrus | R | 12 | 66 | −10 | 31 | −0.004 ± 0.070 | 0.047 ± 0.084 | 0.102 ± 0.112 | 11.1 | SA < HC, NA < HC |
L | 20 | −64 | −8 | 31 | 0.019 ± 0.072 | 0.063 ± 0.101 | 0.113 ± 0.110 | 7.5 | SA < HC | |
L | 31 | −67 | −17 | 19 | 0.005 ± 0.087 | 0.044 ± 0.099 | 0.111 ± 0.137 | 7.8 | SA < HC, NA < HC | |
Middle temporal gyrus | R | 32 | 71 | −29 | 2 | 0.035 ± 0.094 | 0.040 ± 0.098 | 0.176 ± 0.189 | 12.1 | SA < HC, NA < HC |
R | 43 | 69 | −13 | −10 | 0.070 ± 0.139 | 0.61 ± 0.107 | 0.234 ± 0.193 | 14.5 | SA < HC, NA < HC | |
Superior temporal gyrus | R | 22 | 68 | −19 | 18 | 0.035 ± 0.094 | 0.040 ± 0.098 | 0.176 ± 0.189 | 12.3 | SA < HC, NA < HC |
R | 33 | 66 | −4 | 5 | 0.056 ± 0.126 | 0.049 ± 0.112 | 0.192 ± 0.178 | 10.8 | SA < HC, NA < HC | |
R | 44 | 60 | 11 | −8 | 0.075 ± 0.127 | 0.109 ± 0.104 | 0.249 ± 0.193 | 13.4 | SA < HC, NA < HC | |
L | 51 | −57 | 14 | −8 | 0.074 ± 0.177 | 0.111 ± 0.139 | 0.239 ± 0.216 | 7.6 | SA < HC, NA < HC |
Abbreviations: HCs, healthy controls; MDD, major depressive disorder; NAs, non-attempters; SAs, suicide attempters.