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. 2017 Apr 5;12(4):e0175090. doi: 10.1371/journal.pone.0175090

Fig 4. The expression of genes enriched in D2-, but not D1-, enriched striatal neurons are altered by both supplemental DHA and morphine.

Fig 4

A. D1 DHA supplementation did not alter the morphine-induced increase in D1 transcript levels. a, c, d; p<0.001, b; p< 0.05. B. Dyn Neither morphine nor DHA altered the expression of Dyn, a gene enriched in D1-neurons. C. Drd2 Morphine reduced D2 expression while DHA supplementation increased D2 expression following saline or morphine, a; p<0.0, b; p<0.05, c; p<0.001.D. Enk Morphine increased the expression of Enk, a D2-enriched gene. This was reduced following DHA in either morphine or saline treated mice. a; p<0.01, b; p<0.05.