Table 4.
Adjusted associations between VO2Max and neurocognitive functions in regard to prenatal mercury exposure split at the median (23.5 μg/L).
Neurocognitive domain | B (95% CI)a | pdifference | |
---|---|---|---|
Low prenatal exposure (< 23.5 μg/L) | High prenatal exposure (≥ 23.5 μg/L) | ||
Short-term memory | 0.18 (–0.14, 0.50) | 0.18 (–0.23, 0.60) | 0.98 |
Verbal comprehension and knowledge | 0.08 (–0.20, 0.35) | 0.11 (–0.31, 0.52) | 0.91 |
Psychomotor speed | 0.12 (–0.16, 0.40) | –0.07 (–0.38, 0.25) | 0.24 |
Visual processing | 0.11 (–0.21, 0.43) | –0.02 (–0.53, 0.49) | 0.60 |
Long-term storage and retrieval | 0.16 (–0.13, 0.43) | 0.19 (–0.15, 0.52) | 0.90 |
Cognitive processing speed | 0.45 (0.08, 0.81)** | 0.16 (–0.24, 0.56) | 0.20 |
Cognitive efficiency | 0.43 (0.07, 0.80)** | 0.24 (–0.20, 0.68) | 0.53 |
General thinking abilities | 0.15 (–0.17, 0.47) | 0.15 (–0.22, 0.52) | 0.97 |
General function (g) | 0.27 (–0.05, 0.59) | 0.18 (–0.18, 0.54) | 0.69 |
Models were adjusted for sex, physical activity, smoking status, BMI, family background, and prenatal methylmercury exposure. aChange in the standard deviation of the neurocognitive function associated with a 1-SD increase in VO2Max. ** p < 0.05. |