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. 2017 Feb 28;49(1):62–67. doi: 10.3947/ic.2017.49.1.62

Table 1. Comparison of the susceptibility rates for revised and previous clinical and laboratory standards institute (CLSI) for broad-spectrum cephalosporins for Enterobacteriaceae a .

Drug MIC Interpretive Criteria (µg/mL) Zone Diameter Interpretive Criteria (mm)
S SDD I R S SDD I R
Cefotaxime
 Previous ≤8 - 16–32 ≥64 ≥23 - 15–22 ≤14
 Revised ≤1 - 2 ≥4 ≥26 - 23–25 ≤22
Ceftazidime
 Previous ≤8 - 16–32 ≥64 ≥18 - 15–17 ≤14
 Revised ≤4 - 8 ≥16 ≥21 - 18–20 ≤17
Cefepime
 Previous ≤8 - 16 ≥32 ≥18 - 15–17 ≤14
 Revised ≤2 4–8 - ≥16 ≥25 19–24 - ≤18

MIC, minimum inhibitory concentration; S, susceptible; SDD, susceptible-dose dependent; I, intermediate; R, resistant.

aCLSI revised interpretative criteria (breakpoints) for ceftriaxone and ceftazidime in 2011 [1] and interpretative criteria (breakpoints) for cefepime in 2014 [2].