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Coumarins docked to the GTP binding site of MtbFtsZ (2Q1Y) using GOLD software, [a], The GOLD score is given as average of 5 independent runs.
| Compound | GOLD scorea |
|---|---|
| Esculetin | 37.5 |
| Umbelliferone | 35.5 |
| 4-Methylumbelliferone | 32.9 |
| 4-Hydroxycoumarin | 31.8 |
| Coumarin | 31.8 |
| 7-Diethylamino-4- methylcoumarin | 40.1 |
| 6-Methylcoumarin | 39.7 |
| Daphnetin | 42.4 |
| 7-Dimethyl-4-methylcoumarin | 42.8 |
