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. 2017 Mar 1;34(5):890–917. doi: 10.1007/s11095-017-2129-z

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© The Author(s) 2017

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

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Fig. 18 — Simulation results from modelling the liquid penetration in swelling MCC tablets for two different tablet properties (solid line corresponds to ε ₀ = 0.10 and dashed line corresponds to ε ₀ = 0.15). R ₀: initial pore radius; R _c: time-dependent pore radius; ε ₀: initial porosity; ε time-dependent porosity. A modified Carman-Kozeny (see Eq. (5) in [208]) was used to model the permeability as function of porosity.