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. 2017 Mar 1;34(5):890–917. doi: 10.1007/s11095-017-2129-z

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© The Author(s) 2017

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

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Fig. 19 — Modelling the detachment of particles during disintegraton. (a) Layer detachment and progressive tablet expansion. (b) Normalised disintegration (swelling) force depending on time. Curve 1 indicated the results for a tablet consisting of CaHP0₄ ⋅ 2H ₂ O with 1 wt% polyplasdone XL. Curve 2 corresponds to CaHP0₄ ⋅ 2H ₂ O with 20 wt% polyplasdone XL (modified from [197]).