Table 5.

Literature review of the effect of chemical constituents of FAEW against NF-κB.

Compounds	Pharmacological activity on NF-κB
	In vitro	In vivo
Paeoniflorin	Parkinson's disease (Liu et al., 2016a); immunomodulation (Zhai et al., 2016); Alzheimer's disease (Liu et al., 2015); apoptosis (Dong et al., 2015); morphine tolerance (Jiang et al., 2015); anti-inflammation and immunomodulation (Gan et al., 2014); sepsis (Zhang et al., 2014b); obesity (Kong et al., 2013); cardiac remodeling (Zhou et al., 2013)	Renal function (Liu et al., 2016c); non-alcoholic steatohepatitis(Ma et al., 2016); cardiac dysfunction (Zhai and Guo, 2016); vascular dementia (Zhang et al., 2015b); Alzheimer's Disease (Zhang et al., 2015a); arthritis (Yi, 2014); hepatitis (Chen et al., 2015); colitis (Zhang et al., 2014a); learning dysfunction and brain damage (Guo et al., 2012); lung injury (Zhou et al., 2011)
Baicalin	Myofibroblast differentiation (Shin et al., 2016); atherosclerosis (Wang et al., 2016a); haemophilus parasuis infection (Fu et al., 2016); mastitis (Guo et al., 2013); apoptosis (Yang et al., 2016b)	Asthma (Liu et al., 2016b); periodontitis (Sun et al., 2016); allergic diseases (Zhou et al., 2016b); arthritis (Wang et al., 2014); brain edema (Zhou et al., 2014); lung injury (Ding et al., 2016); liver injury (Wan et al., 2008); ischemic stroke (Singh and Chopra, 2014); cerebral ischemia (Tu et al., 2011)
Isoliquiritin	Inflammatory responses (Kim et al., 2008)
Liquiritin	Endothelial dysfunction (Zhang et al., 2013)	Myocardial fibrosis (Zhang et al., 2016c); acute Lung Injury (Tao et al., 2016)
Oroxyloside		Colitis (Wang et al., 2016d)