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. 2017 Apr 5;8:14805. doi: 10.1038/ncomms14805

Figure 3. Effects of acute TNF scavenging on systemic haemodynamics.

Figure 3

Radiotelemetric haemodynamic measurements of sham-operated mice. (a) MAP and (b) heart rate in sham-operated mice injected with etanercept (ETN, 20 mg kg−1 i.p., arrow, n=4 sham mice). (c) MAP and (d) heart rate measurements of mice with HF induced by left anterior descending coronary artery ligation and injected with ETN (20 mg kg−1 i.p., arrow, n=4 mice). (e) MAP and (f) heart rate measurements of naive (non-operated) wild-type mice injected with boiled etanercept (boiled ETN, 20 mg kg−1 i.p., arrow, n=4 mice). (g) MAP and (h) heart rate of sham-operated mice injected with saline (100 ul, arrow, n=4 mice). (i) MAP and (j) heart rate of HF mice injected with saline (100 ul, arrow, n=4 mice). (k) MAP and (l) heart rate of naive (non-operated) wild-type mice injected with saline (100 ul, arrow, n=8 mice). All data are mean±s.e.m. *P<0.05 for one-way repeated-measures ANOVA and Dunnett's post hoc test relative to 0 h. ANOVA, analysis of variance.