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. 2017 Apr 5;9:35. doi: 10.1186/s13148-017-0336-4

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© The Author(s). 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 4 — Genomic location of sig-DMPs. DMPs were mapped to gene elements (top left), CpG islands (top right), and chromatin state segmentations (bottom). Asterisks indicate significant enrichment or depletion in comparison with all Illumina probes (gray bars) measured by the Fisher’s exact test (P value < 0.05). Sig–DMPs where the interaction term was significant (blue bars) showed an enrichment in promoter regions and CpG islands. Sig-DMPs where no interaction was seen (orange bars) showed no significant enrichment or depletion in a particular genomic region