Table 1.
Baseline and demographic data. Data are expressed as percentage (frequency) or median (IQR)
| Ticagrelor (n = 142) | Clopidogrel (n = 259) | p | |
|---|---|---|---|
| Age (years) | 66 (56–73) | 67 (56–67) | 0.206 |
| Age ≥ 75 years | 21.8 (31) | 32.0 (83) | 0.037 |
| Sex male | 73.9 (105) | 69.9 (81) | 0.420 |
| BMI (kg/m2)a | 26 (24–30) | 26 (24–29) | 0.772 |
| Hypertension | 52.8 (75) | 56.0 (145) | 0.600 |
| Dyslipidemia | 36.6 (52) | 39.0 (101) | 0.668 |
| Active smoke | 45.8 (65) | 37.8 (98) | 0.137 |
| Diabetes mellitus | 22.5 (32) | 18.5 (48) | 0.362 |
| Familiar of CAD | 21.1 (30) | 24.7 (64) | 0.461 |
| Previous stable angina | 11.3 (16) | 6.6 (17) | 0.128 |
| Previous unstable angina | 3.5 (5) | 4.6 (12) | 0.797 |
| Previous AMI | 11.3 (16) | 11.2 (29) | 1.000 |
| Previous PCI | 7.0 (10) | 9.3 (24) | 0.574 |
| Previous CABG | 1.4 (2) | 0.0 (0) | 0.125 |
| Previous CVA | 4.9 (7) | 7.3 (19) | 0.403 |
| PVD | 16.2 (23) | 11.2 (29) | 0.164 |
| Chronic kidney disease | 7.0 (10) | 4.6 (12) | 0.361 |
| COPD | 8.5 (12) | 8.9 (23) | 1.000 |
| Previous bleeding | 0.7 (1) | 3.9 (10) | 0.106 |
| Previous neoplasia | 10.6 (15) | 15.8 (41) | 0.175 |
Italics: p value ≤0.05
BMI body mass index, CAD coronary artery disease, AMI acute myocardial infarction, PCI percutaneous coronary intervention, CABG coronary artery bypass grafting, CVA cerebrovascular accident, PVD peripheral vascular disease, COPD chronic obstructive pulmonary disease
a n = 139 for ticagrelor, 258 for clopidogrel