Table 2.
Clinical presentation and reperfusion strategy. Data are expressed as percentage (frequency), median (IQR), or mean (SD)
| Ticagrelor | Clopidogrel | p | |
|---|---|---|---|
| Call to emergency service | 43.0 (61/142) | 41.3 (107/259) | 0.75 |
| Secondary transfer by emergency service | 40.8 (58/142) | 40.3 (104/258) | 0.92 |
| Hub vs spoke | 67.1 (94/140) | 64.5 (167/259) | 0.65 |
| Anterior AMI | 46.5 (66/142) | 39.8 (103/259) | 0.21 |
| New LBBB at first EKG | 2.3 (5/142) | 3.5 (6/256) | 0.53 |
| Cardiac frequency (bpm) | 75 (65–88) | 77 (63–94) | 0.28 |
| Systolic blood pressure (mmHg) | 140 (120–160) | 140 (120–160) | 0.76 |
| Killip class ≥ 3 | 5.6 (8/142) | 8.1 (21/259) | 0.42 |
| Cardiac arrest | 2.1 (3/142) | 3.1 (8/259) | 0.75 |
| LV ejection fraction (%) | 46 (40–55) | 45 (40–55) | 0.83 |
| GFR Cockroft Gault (mL/min/m2) | 72 (55–90) | 67 (52–86) | 0.08 |
| GFR MDRD (mL/min/m2) | 76 ± 25 | 72 ± 23 | 0.09 |
| GRACE-in-hospital mortality | 139 (122–157) | 141 (121–167) | 0.32 |
| GRACE 6-month mortality | 106 (86–128) | 106 (87–125) | 0.96 |
| TIMI risk score | 3 (2–5) | 4 (2–5) | 0.18 |
| CRUSADE | 23 (14–36) | 27 (18–38) | 0.015 |
| Thrombolysis | 1.8 (4/142) | 4.6 (12/259) | 0.44 |
| Coronary angiography | 100.0 (142/142) | 93.1 (241/259) | 0.001 |
| PCI | 92.3 (131/142) | 80.7 (209/259) | 0.002 |
| Primary PCI (≤12 h after first medical contact) | 82.4 (117/142) | 66.4 (172/259) | 0.001 |
| IABP | 0.7 (1/142) | 3.1 (8/259) | 0.17 |
Italics: p value ≤0.05
AMI acute myocardial infarction, LBBB left bundle branch block, EKG, electrocardiogram, LV left ventricle, GFR glomerular filtration rate, MDRD modification of diet in renal disease, GRACE global registry of acute coronary events, TIMI thrombolysis in myocardial infarction, CRUSADE can rapid risk stratification of unstable angina patients suppress adverse outcome with early implementation of ACC/AHA Guidelines, PCI percutaneous coronary intervention, IABP intra-aortic balloon pump