Table 2.

Univariate Cox regression analysis for cardiovascular outcome

	All (n = 320)		T2DM (−) (n = 184)		T2DM (+) (n = 136)
	HR (95% CI)	p value	HR (95% CI)	p value	HR (95% CI)	p value
Age, per 1SD	1.65 (1.26–2.17)	<0.001	1.42 (0.94–2.15)	0.09	1.82 (1.25–2.63)	0.002
Male gender	1.45 (0.87–2.41)	0.2	0.69 (0.26–1.84)	0.5	1.85 (0.97–3.53)	0.06
BMI, per 1SD	0.84 (0.65–1.09)	0.2	0.82 (0.55–1.23)	0.3	0.84 (0.60–1.18)	0.3
Hypertension	2.04 (1.12–3.70)	0.02	2.75 (1.03–7.33)	0.04	1.47 (0.69–3.11)	0.3
Hyperlipidemia	0.81 (0.49–1.34)	0.4	0.76 (0.34–1.67)	0.5	0.74 (0.39–1.40)	0.4
Previous CAD	1.54 (0.90–2.64)	0.12	2.19 (0.98–4.88)	0.055	1.24 (0.59–2.64)	0.6
Previous stroke	1.07 (0.53–2.16)	0.9	1.62 (0.61–4.31)	0.3	0.74 (0.26–2.09)	0.6
LVEF (%), per 1SD	0.70 (0.55–0.88)	0.003	0.61 (0.43–0.86)	0.005	0.87 (0.63–1.20)	0.4
HbA1C, per 1SD	1.32 (1.06–1.63)	0.01	0.82 (0.51–1.31)	0.4	1.14 (0.82–1.57)	0.4
log10(TG), per 1SD	0.92 (0.72–1.19)	0.5	0.89 (0.60–1.33)	0.6	0.82 (0.58–1.15)	0.2
TC, per 1SD	0.87 (0.67–1.13)	0.3	0.94 (0.62–1.42)	0.8	0.80 (0.58–1.11)	0.2
HDL-C, per 1SD	0.95 (0.73–1.23)	0.7	0.81 (0.52–1.27)	0.4	1.05 (0.77–1.44)	0.8
LDL-C, per 1SD	0.88 (0.68–1.14)	0.3	1.06 (0.71–1.57)	0.8	0.77 (0.56–1.07)	0.12
GFR, per 1SD	0.60 (0.48–0.74)	<0.001	0.65 (0.47–0.90)	0.008	0.57 (0.42–0.77)	<0.001
CK-MB, per 1SD	1.01 (0.79–1.31)	0.9	1.16 (0.86–1.57)	0.3	0.85 (0.56–1.31)	0.5
Troponin I, per 1SD	1.30 (1.10–1.54)	0.002	1.23 (0.92–1.66)	0.2	1.33 (1.10–1.62)	0.004
hsCRP, per 1SD	1.84 (1.43–2.37)	<0.001	1.77 (1.20–2.60)	0.004	1.75 (1.25–2.46)	0.001
log10(PAPP-A), per 1SD	3.10 (2.48–3.87)	<0.001	3.16 (2.27–4.39)	<0.001	2.97 (2.11–4.18)	<0.001

HR hazard ratio, CI confidence interval, LVEF (%) percentage of LVEF >50%, other abbreviations as in Table 1