Table 4.

Area under the ROC curve (AUC) for PAPP-A, other selected factors and a multivariate model (all factors)

	All (n = 320)		T2DM (−) (n = 184)		T2DM (+) (n = 136)
	AUC (95% CI)	p value	AUC (95% CI)	p value	AUC (95% CI)	p value
PAPP-A	0.80 (0.74–0.87)	Ref.	0.78 (0.67–0.88)	Ref.	0.79 (0.70–0.87)	Ref.
Diabetes	0.61 (0.54–0.67)	<0.001
Age	0.65 (0.58–0.73)	0.003	0.60 (0.48–0.72)	0.051	0.69 (0.59–0.79)	0.15
LVEF (%)	0.60 (0.52–0.68)	<0.001	0.66 (0.54–0.77)	0.06	0.52 (0.40–0.64)	<0.001
eGFR	0.66 (0.58–0.74)	<0.001	0.64 (0.52–0.76)	0.051	0.66 (0.56–0.77)	0.03
hsCRP	0.68 (0.60–0.75)	0.003	0.69 (0.57–0.80)	0.2	0.64 (0.52–0.76)	0.01
Multivariate (all above)	0.83 (0.77–0.89)	0.12	0.80 (0.70–0.90)	0.2	0.83 (0.75–0.91)	0.051

AUC areas under the receiver operating characteristics curve, Multivariate a multivariate logistic regression using all factors presented in this table, p value comparison to the PAPP-A model; Ref. reference