Table 3.
Correlation Analysis for Percent Change at Week 52 and Baseline Demographics (mITT population)
| Percent Change sCD14 | Percent Change oxLDL | Percent Change Lp-PLA2 | |
|---|---|---|---|
| Age | ρ= −0.07 P= 0.36 |
ρ= −0.07 P=0.32 |
ρ= −0.11 P=0.12 |
| Framingham Risk Score | ρ= −0.09 P=0.23 |
ρ= 0.05 P=0.48 |
ρ= −0.04 P=0.60 |
| CD4 count | ρ= 0.09 P=0.22 |
ρ= −0.01 P=0.87 |
ρ=0.02 P=0.74 |
| Log HIV-1 Viral Load | ρ= 0.04 P=0.54 |
ρ= 0.06 P=0.43 |
ρ=0.14 P=0.06 |
| LDL-C | ρ= −0.01 P=0.87 |
ρ= −0.17 P=0.02 |
ρ= −0.27 P=0.0002 |
| sCD14 | ρ= −0.48 P < 0.0001 |
ρ= −0.08 P=0.25 |
ρ= −0.03 P=0.67 |
| oxLDL | ρ= −0.02 P=0.75 |
ρ= −0.33 P < 0.0001 |
ρ= −0.03 P=0.66 |
| Lp-PLA2 | ρ= −0.04 P=0.56 |
ρ= 0.03 P=0.65 |
ρ= −0.27 P=0.0002 |
Significant P-values are shown in bold. Data are shown for mITT population with biomarker specimens available for Week 52.
Abbreviations: LDL-C, low density lipoprotein cholesterol; sCD14, soluble CD14; oxLDL, oxidized low density lipoprotein, Lp-PLA2, lipoprotein-associated phospholipase A