Figure 1. Radio frequency (RF) radiation-induced hyperthermia using RF-absorbing Si nanoparticle-based sensitizers.

(a) Schematic representation of the treatment procedure. The nanoparticles are first selectively accumulated in tumor cells through passive or active targeting. Then, they are heated by RF radiation causing a local increase of temperature and selective death of cancer cells, while adjacent tissues remain unaffected, (b) Distribution of electric field around a solid polarizable sphere immersed in a liquid electrolyte (water) during RF irradiation. A dipolar charge cloud is formed due to the ion movement in electrical double layer in response to RF-induced sphere polarization.