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. 2017 Mar;23(3):423–429. doi: 10.3201/eid2303.160679

Table. Description of lineage and associated rpoB, katG, and fabG1-InhA mutation identifiers in drug-resistant Mycobacterium tuberculosis isolates, Congo*.

Isolate code Resistance Gene Nucleotide change Amino acid substitutions Lineage
8032/11
INH, STR
katG
AGC-315-ACC
Ser-315-Thr
Congo type
8114/11 INH, RIF, STR, EMB, PZA, ETH katG AGC-315-ACC Ser-315-Thr Uganda I
rpoB GAC-516-GTC Asp-516-Val


inhA
−102G/A
NA

8125/11 INH, RIF, STR, EMB, PZA katG AGC-315-ACC Ser-315-Thr Beijing
rpoB GAC-516-TAC Asp −516- Tyr

*EMB, ethambutol; ETH, ethionamide; INH, isoniazid; NA, not applicable; PZA, pyrazinamide; RIF, rifampin; STR, streptomycin.