Table. Description of lineage and associated rpoB, katG, and fabG1-InhA mutation identifiers in drug-resistant Mycobacterium tuberculosis isolates, Congo*.
Isolate code | Resistance | Gene | Nucleotide change | Amino acid substitutions | Lineage |
---|---|---|---|---|---|
8032/11 |
INH, STR |
katG
|
AGC-315-ACC |
Ser-315-Thr |
Congo type |
8114/11 | INH, RIF, STR, EMB, PZA, ETH | katG | AGC-315-ACC | Ser-315-Thr | Uganda I |
rpoB | GAC-516-GTC | Asp-516-Val | |||
|
|
inhA
|
−102G/A |
NA |
|
8125/11 | INH, RIF, STR, EMB, PZA | katG | AGC-315-ACC | Ser-315-Thr | Beijing |
rpoB | GAC-516-TAC | Asp −516- Tyr |
*EMB, ethambutol; ETH, ethionamide; INH, isoniazid; NA, not applicable; PZA, pyrazinamide; RIF, rifampin; STR, streptomycin.