FIG 1.

Mean levels of parasitemia in Aotus monkeys immunized in a prime/boost regimen with plasmid DNA/Ad5 encoding P. vivax blood-stage antigens AMA1 and MSP1₄₂ and challenged with P. vivax SAL-1. Group A, plasmid/virus control (n = 4); group B, AMA1/AMA1 (n = 5); group C, MSP1₄₂/MSP1₄₂ (n = 5); group D, AMA1-MSP1₄₂/AMA1-MSP1₄₂ (n = 5); group E, control/AMA1-MSP1₄₂ (n = 4); group F, AMA1-MSP1₄₂/control (n = 4); group G, infection control (n = 2). A level of parasitemia of 0.001 × 10³ parasites/μl was considered negative or undetectable by microscopy.