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. 2017 Apr 6;7:45317. doi: 10.1038/srep45317

Table 3. Loci associated with bone traits in crossbred layer population.

Chromosome SNP Physical positiona Minor/major Allele Minor Allelic Frequency Candidate gene SNP location Proportion phenotypic variance Betab SEc P Value Trait
1 rs312784357 165885243 A/G 0.480 RANKL intergenic 0.050 -0.298 0.057 3.09E-07 BMC
1 rs312550725 169381724 T/C 0.405 SERPINE3 missense 0.013 0.226 0.047 4.71E-08 Breaking strength
1 rs317281616 169400244 G/A 0.307 INTS6 intron 0.030/0.056 0.275/0.345 0.049/0.055 1.29E-08/5.86E-10 Breaking work/BMC
1 rs13975174 171298203 A/G 0.370 POSTN intron 0.077 −0.293 0.050 2.88E-12 Femoral weight
4 rs14491507 76073771 A/G 0.052 TAPT1 intergenic 0.024 0.479 0.090 1.11E-07 BMC
4 rs15620367 76186390 A/G 0.130 FGFBP1 intron 0.023 0.333 0.066 5.51E-07 Femoral weight
14 rs313699988 11876668 T/C 0.126 GSG1L intergenic 0.023 0.315 0.062 4.18E-07 BMD
24 rs315096388 1684374 T/C 0.177 ADAMTS15 intergenic 0.014 0.215 0.051 2.43E-07 Breaking strength
27 rs316237751 3200813 G/C 0.087 SOST intergenic 0.031 0.430 0.071 1.59E-09 BMC
27 rs316723909 3464323 G/A 0.087 IGF2BP1 intergenic 0.041 0.500 0.072 5.01E-12 Femoral weight

aPhysical position is bp location on chromosome for NCBI Gallus_gallus-4.0. bEstimates presented for allelic substitution effect per copy of the effect allele (EA) under an additive model, expressed in SD unit/allele.

cSE is the standard error of the beta.