Table 2. Parameters needed for log rank test calculations obtained in an example data set of myelofibrosis patients.
N |
Time (months) |
Status | Group | I | O | R | RGr1 | RGr2 | EGr1 | EGr2 | VMantel* | O/R | Λ† | W‡ | W2 |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | 0.10 | 0 | 1 | 1 | 0 | 67 | 41 | 26 | 0.00 | 0.00 | 0.00 | ||||
2 | 0.57 | 1 | 1 | 2 | 1 | 66 | 40 | 26 | 0.61 | 0.39 | 0.24 | 0.02 | 0.02 | 0.98 | 0.97 |
3 | 0.60 | 1 | 2 | 3 | 1 | 65 | 39 | 26 | 0.60 | 0.40 | 0.24 | 0.02 | 0.03 | 0.97 | 0.94 |
4 | 1.17 | 1 | 1 | 4 | 1 | 64 | 39 | 25 | 0.61 | 0.39 | 0.24 | 0.02 | 0.05 | 0.95 | 0.91 |
5 | 1.47 | 1 | 1 | 5 | 1 | 63 | 38 | 25 | 0.60 | 0.40 | 0.24 | 0.02 | 0.06 | 0.94 | 0.88 |
6 | 1.57 | 1 | 2 | 6 | 1 | 62 | 37 | 25 | 0.60 | 0.40 | 0.24 | 0.02 | 0.08 | 0.92 | 0.85 |
7 | 1.70 | 1 | 2 | 7 | 1 | 61 | 37 | 24 | 0.61 | 0.39 | 0.24 | 0.02 | 0.09 | 0.91 | 0.82 |
8 | 2.17 | 0 | 1 | 7 | 1 | 61 | 37 | 24 | 0.09 | 0.09 | 0.01 | ||||
9 | 2.23 | 0 | 2 | 7 | 1 | 61 | 37 | 24 | 0.09 | 0.09 | 0.01 | ||||
10 | 4.90 | 1 | 2 | 8 | 1 | 58 | 36 | 22 | 0.62 | 0.38 | 0.24 | 0.02 | 0.11 | 0.89 | 0.79 |
The first ten observations are shown. For specific calculations please see Table 1 and the supplementary file. N – number of observation. Time - duration of follow-up, recorded in months in our example. Status - censoring variable, 1 for death and 0 for alive or lost to follow-up. Group - 1 for grade < 3 myelofibrosis and 2 for grade 3 myelofibrosis patients. I – number of interval. O – observed number of deaths per interval. R – overall number at risk per interval. RGr1 and RGr2 – overall number at risk in a specific group per interval. EGr1 and EGr2 – expected number of deaths in a specific group per interval. * Variance of the log-rank test calculated by Mantel method. †Λ – the Nelson-Aalen estimator. ‡W – score for the Peto log-rank test. |