Table 2. A comparison of proteins and enriched GO processes that were identified through conservation or rapid evolution of sequence or of inferred PPIs.

	# Proteins	# Enriched GO Terms
Conserved
Low ω	418	87
Low γ	936	101
Overlap	108	15
Rapidly changing
High ω	123	7
High γ	191	12
Overlap	9	1

“Conserved” sequence refers to the 10% of genes with the lowest ω, while “positively selected” refers to 123 proteins inferred to be under positive selection. Unusually high or low γ includes proteins whose true γ is above (rapidly changing) or below (conserved) the distribution of γ from the simulated datasets. Enriched GO processes (p<0.05) are included. Details regarding the proteins/GO terms found in each set can be found in S8 Table.