Fig. 8.
Caspase activity of control HeLa cells or HeLa cells with combined knockdown of MCU and Letm1, normalized to corresponding control conditions as percentage of viable cells, was measured via Caspase 3/7-Glo assay following the standard protocol after 36 h of compound incubation (A). Cell viability of control HeLa cells or HeLa cells with combined knockdown of MCU and Letm1 was determined using Celltiter-Blue assay according to the standard protocol after 36 h of incubation with resveratrol [100 µM], piceatannol [100 µM], or oligomycin A [10 µM] and calculated as percentage of viable cells in comparison to corresponding control cells (B).