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. 2017 Apr 6;12(4):e0174706. doi: 10.1371/journal.pone.0174706

Fig 2. Workflow to identify and validate chemical matter that inhibits KRAS activation of BRAF through direct interaction with KRAS.

Fig 2

Green boxes utilize full-length prenylated KRAS in a lipid environment, yellow boxes utilize truncated KRAS in aqueous buffer and the grey box is the BRAFV600E counter-screen.